<p>The present invention relates to processes for epimerising alcohols of compounds having a hydroxyl substituent on an asymmetric allylic carbon, such as compounds useful for the synthesis of vitamin D analogues where the epimeric hydroxyl substituent is at the 24 position. The invention further relates to methods of producing intermediates useful for the synthesis of calcipotriol by said epimerisation processes.</p>
申请公布号
WO2006024296(A1)
申请公布日期
2006.03.09
申请号
WO2005DK00533
申请日期
2005.08.22
申请人
LEO PHARMA A/S;PEDERSEN, HENRIK;BRETTING, CLAUS, AAGE, SVENSGAARD;BINDERUP, ERNST, TORNDAL