Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor

摘要

The present invention relates to anti-idiotypic antibodies which induce an immune response against tumors, bearing as antigen the epidermal growth factor receptor (EGFR). The antibodies of the invention may mimick said antigen. As preferred embodiment the antibodies of the invention derive from mAb 425 (ATCC HB 9629) or a humanized or chimeric derivative thereof.