发明名称 |
Pyridine derivatives with IKB-kinase (IKK-beta) inhibiting activity |
摘要 |
Pyridine derivative compounds of formula (I) with IKB kinase beta (IKK-beta) inhibiting activity are disclosed, wherein R1, R2, R3, R4 and R5 are as defined in the specification. These compounds have an excellent anti-inflammatory activity, and other biological activity, wherein these compounds can be used as an immunosuppressant, an agent to treat ischemia, an anti-tumoral agent, an agent for treating asthma, and for treating such other diseases.
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申请公布号 |
NZ535056(A) |
申请公布日期 |
2006.02.24 |
申请号 |
NZ20010535056 |
申请日期 |
2001.09.10 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
MURATA, TOSHIKI;UMEDA, MASAOMI;SAKAKIBARA, SACHIKO;YOSHINO, TAKASHI;SATO, HIROKI;MASUDA, TSUTOMU;KORIYAMA, YUJI;SHIMADA, MITSUYUKI;SHINTANI, TAKUYA;KADONO, HIROSHI;LOWINGER, TIMOTHY B;ZIEGELBAUER, KARL B;FUCHIKAMI, KINJI;KOMURA, HIROSHI |
分类号 |
(IPC1-7):C07D513/04;C07D498/04;C07D413/14;C07D521/00;C07D405/14;C07D471/04;C07D409/14;C07D213/85;C07D401/04;C07D471/18;C07D401/14;C07D213/73;C07D401/06;C07D213/80;A61K31/435;A61K31/442;A61P11/06;A61P17/00;A61P29/00 |
主分类号 |
(IPC1-7):C07D513/04 |
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