| 摘要 |
The present invention relates to an abuse-proofed oral dosage form with controlled release of (1R,2R)-3(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol for once daily administration, characterised in that it comprises the active ingredient and/or one or more of the pharmaceutically acceptable salts thereof (A), at least one synthetic or natural polymer (C), delayed-release auxiliary substances, optionally physiologically acceptable auxiliary substances (B) and optionally a wax (D), component (C) or (D) in each case exhibiting a breaking strength of at least 500 N, preferably of at least 1000 N.
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