发明名称 |
Method for determination of thymidine kinase 1 activity and the use thereof |
摘要 |
The present invention concerns a new method that enables safe, rapid, accurate and specific determination of thymidine kinase 1 activity in human or animal body fluids and tissue/cell extracts for routine analysis of samples with low levels of activity by using AZT or 3' derivatives of thymidine as substrate and determining the phosphorylated products formed in the reaction with thymidine kinase 1 activity. The invention further relates to the use of said method for the diagnosis, monitoring and prognostics of diseases such as cancer.
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申请公布号 |
US2006035295(A1) |
申请公布日期 |
2006.02.16 |
申请号 |
US20050522870 |
申请日期 |
2005.06.13 |
申请人 |
OEHRVIK ANDERS;ERIKSSON STAFFAN |
发明人 |
OEHRVIK ANDERS;ERIKSSON STAFFAN |
分类号 |
G01N33/53;G01N33/537;C07D405/04;C12Q1/48;G01N21/76;G01N33/543;G01N33/573;G01N33/574 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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