EXTRACTS OF: PHOLIDOTA CHINESIS LINDL. THE PREPARATION METHODS AND PHARMACEUTICAL USE THEREOF

摘要

This invention relates to extracts of Pholidota Chinesis Lindl. the preparation methods and pharrriaceutical use thereof. The methods of extracting active compound from Pholidota Chinesis Lindl. incudes the following steps: 1) extracting the Pholidota Chinesis Lindl. by ethanol, concentrating at reduced pressure to make extractive; 2) ectracting the extractive in turn of n-butane, ethyl acetate, n-butanol; 3) directing the extractive of ethyl acetate through chromatography column, eluting by methanol;4) separating and purifying the elent collected in step 3) by high pressure liquid chromatography to get active compounds. The formula of the extracted active compound (3-10) is: (I); active compound (1) is: (II); active compound (2) is: (III). The compound or its salts, enantiomers, racemes, tautomers and physiologic functional derivates extracted from the Pholidota Chinesis Lindl. Are useful in production of the medicament for the treatment or prevention of inflammatory disease.