发明名称 |
ACTRII RECEPTOR POLYPEPTIDES, METHODS AND COMPOSITIONS |
摘要 |
In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of a tissue, such as bone, cartilage, muscle, fat, and/or neuron. The present invention also provides methods of screening compounds that modulate activity of an ActRII protein and/or an ActRII ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRII protein and/or an ActRII ligand. |
申请公布号 |
WO2006012627(A2) |
申请公布日期 |
2006.02.02 |
申请号 |
WO2005US26368 |
申请日期 |
2005.07.25 |
申请人 |
ACCELERON PHARMA INC.;KNOPF, JOHN;SEEHRA, JASBIR |
发明人 |
KNOPF, JOHN;SEEHRA, JASBIR |
分类号 |
C07K14/705;A61K38/17;A61P19/00;A61P21/00;A61P25/00 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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