| 发明名称 |
Pyrrolidin-Derivate. |
| 摘要 |
Pyrrolidine muscarinic receptor antagonists, particularly useful in the treatment of irritable bowel syndrome, of the formula:- <CHEM> and their pharmaceutically acceptable salts, wherein Y is a direct link, -CH2-, -(CH2)2-, -CH2O- or -CH2S-; R is -CN or -CONH2; and R<1> is a group of the formula:- <CHEM> where X and X<1> are each independently O or CH2; m is 1, 2 or 3; and "Het" is pyridyl, pyrazinyl or thienyl. u |
| 申请公布号 |
DE122005000022(I2) |
申请公布日期 |
2006.02.02 |
| 申请号 |
DE20051200022C |
申请日期 |
1990.03.02 |
| 申请人 |
NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. |
发明人 |
CROSS, PETER EDWARD, DR.;MACKENZIE, ALEXANDER RODERICK, D. |
| 分类号 |
A61K31/40;A61K31/4025;A61K31/435;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61P1/00;A61P11/00;A61P25/02;C07D207/06;C07D207/08;C07D207/09;C07D401/06;C07D401/12;C07D403/06;C07D403/12;C07D405/06;C07D405/12;C07D409/06;C07D409/12 |
主分类号 |
A61K31/40 |
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