发明名称 Benzoxazol derivatives
摘要 The invention relates to compounds of formula wherein R is phenyl, unsubstituted or substituted by halogen or -CH<SUB>2</SUB>N(CH<SUB>3</SUB>)(CH<SUB>2</SUB>)<SUB>n</SUB>OCH<SUB>3</SUB>, or is benzyl, lower alkyl, lower alkoxy, -(CH<SUB>2</SUB>)<SUB>n</SUB>OCH<SUB>3</SUB>, or is pyridin 3 -or 4-yl, unsubstituted or substituted by lower alkyl, halogen, morpholinyl, -(CH<SUB>2</SUB>)<SUB>n</SUB>-halogen, -(CH<SUB>2</SUB>)<SUB>n</SUB>OCH<SUB>3</SUB>, -(CH<SUB>2</SUB>)<SUB>n</SUB>-morpholin-4-yl, or -(CH<SUB>2</SUB>)<SUB>n</SUB>-pyrrolidin-1-yl; R<SUP>1 </SUP>is phenyl, unsubstituted or substituted by halogen, tetrahydropyran-4-yl, 3,6-dihydro-2H-pyran-4-yl or morpholin-4-yl; n is independently from each other 1 or 2; and to pharmaceutically acceptable salts thereof for the treatment of diseases related to the adenosine A<SUB>2A</SUB>-receptor.
申请公布号 US6992083(B2) 申请公布日期 2006.01.31
申请号 US20040755105 申请日期 2004.01.09
申请人 HOFFMAN-LA ROCHE INC. 发明人 NORCROSS ROGER DAVID
分类号 C07D263/58;A61K31/421;A61K31/423;A61K31/4439;A61P25/28;C07D265/30;C07D413/04;C07D413/12;C07D413/14 主分类号 C07D263/58
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