发明名称 ПИРАЗОЛХИНОЛИНЫ С ИММУНОМОДУЛИРУЮЩЕЙ АКТИВНОСТЬЮ
摘要 The present invention relates to novel heterocyclic compounds of the formula (I), to methods for their preparation, to compositions containing them, and to methods and use for clinical treatment of medical conditions which may benefit from immunomodulation, including rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosis and psoriasis. More particularly the present invention relates to novel heterocyclic compounds, which are CD80 antagonists capable of inhibiting the interactions between CD80 and CD28.
申请公布号 RU2005119639(A) 申请公布日期 2006.01.20
申请号 RU20050119639 申请日期 2003.11.21
申请人 ЭКТИВ БАЙОТЕК АБ (SE) 发明人 МЭТТЬЮЗ Иэн Ричард (GB);КОУЛТЕР Томас Стивен (GB);ГИРОН Чиара (GB);БРЕННАН Крис Джеймс (GB);УДДИН Мухаммед Камаль (GB);ПЕТТЕРССОН Ларс Олоф Йеран (SE);ТРИГЕ Дорте Да Граса (SE);ХАКСЛИ Филип (GB)
分类号 C07D471/06;A61K31/4162;A61K31/4745;A61P37/02;C07D471/04;C07D491/04;C07D495/04;C07D519/00;G07D 主分类号 C07D471/06
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