| 发明名称 |
NOGO-RECEPTOR ANTAGONISTS FOR THE TREATMENT OF CONDITIONS INVOLVING AMYLOID PLAQUES |
| 摘要 |
<p>The invention provides methods for treating diseases involving aberrant amyloid-beta (Abeta) peptide deposition, including Alzheimer's Disease, by the administration of Nogo receptor antagonists. The invention also provides method for reducing levels of Abeta peptide in a mammal by the administration of soluble Nogo receptor polypeptides</p> |
| 申请公布号 |
EP1615654(A2) |
申请公布日期 |
2006.01.18 |
| 申请号 |
EP20040759905 |
申请日期 |
2004.04.16 |
| 申请人 |
YALE UNIVERSITY;BIOGEN IDEC MA, INC. |
发明人 |
LEE, DANIEL, H.S.;LI, WEIWEI;STRITTMATTER, STEPHEN M. |
| 分类号 |
A61K38/00;A61K38/17;A61P25/28;C07K16/28;(IPC1-7):A61K38/02;A61K38/16 |
主分类号 |
A61K38/00 |
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