| 发明名称 |
Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes |
| 摘要 |
<p>The present invention relates to certain substituted heterocycles of Formula (I) which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, adipocyte differentiation, uncontrolled proliferation, such as lymphoma, Hodgkin's Disease, leukemia, breast cancer, prostate cancer or cancers in general; and inflammation, such as osteoarthritis, rheumatiod arthritis, Crohn's Disease or Inflammatory Bowel Disease.
<Chemistry id="chema01" num="0001"><Image id="ia01" he="48" wi="78" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry></p> |
| 申请公布号 |
EP1593677(A3) |
申请公布日期 |
2006.01.04 |
| 申请号 |
EP20050017383 |
申请日期 |
2000.08.31 |
| 申请人 |
INCYTE SAN DIEGO INCORPORATED;ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
PFAHL, MAGNUS;TACHDJIAN, CATHERINE;AL-SHAMMA, HUSSIEN A.;FANJUL, ANDREA;PLEYNET, DAVID P. M.;SPRUCE, LYLE W. |
| 分类号 |
A61K31/4439;C07D277/34;A61K31/4166;A61K31/42;A61K31/426;A61P3/10;C07D233/40;C07D233/42;C07D233/78;C07D233/86;C07D233/96;C07D261/12;C07D277/36;C07D401/06;C07D401/10;C07D403/10;C07D405/10;C07D417/06;C07D417/10 |
主分类号 |
A61K31/4439 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
