发明名称 |
COUPLED COFACTOR-DEPENDENT ENZYMATIC REACTION SYSTEMS IN AQUEOUS MEDIA |
摘要 |
The present application relates to a reaction system in which chemically valuable compounds can be obtained in high enantiomer concentrations with the aid of a coupled enzymatically operating transformation process. The coupled enzymatic reaction system comprises a cofactor-dependent enzymatic transformation of an organic compound and an enzymatic regeneration of the cofactor, wherein the reaction system operates in aqueous solution with an amount of substrate above the solubility limit thereof. In the preferred embodiments, an alcohol dehydrogenase is the cofactor-dependent enzyme, and the regeneration of the cofactor (e.g. NADH or NADPH) is acheved by means of formate dehydrogenase. |
申请公布号 |
EP1606412(A1) |
申请公布日期 |
2005.12.21 |
申请号 |
EP20040721168 |
申请日期 |
2004.03.17 |
申请人 |
DEGUSSA AG |
发明人 |
GRÖGER, HARALD;ROLLMANN, CLAUDIA;HÜSKEN, HENDRIK;WERNER, HELGE;CHAMOULEAU, FRANÇOISE;HAGEDORN, CHAD;DRAUZ, KARLHEINZ;HUMMEL, WERNER |
分类号 |
C12N9/02;C12P7/02;C12P7/22 |
主分类号 |
C12N9/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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