| 摘要 |
FIELD: medicine, chemistry of peptides, amino acids. ^ SUBSTANCE: invention relates to novel biologically active substances. Invention proposes the novel composition comprising peptides of the formula: H-Arg-Gly-Asp-OH and H-Tyr-X-Y-Glu-OH wherein X means Gln and/or Glu; Y means Cys(acm) and/or Cys. The composition shows ability to inhibit proliferative activity of mononuclear cells, to induce suppressive activity and their ability for secretion of cytokines TNF-1beta (tumor necrosis factor-1beta) and IL-10 (interleukin-10 ). ^ EFFECT: simplified method for preparing composition, valuable medicinal properties of composition. ^ 4 cl, 16 tbl, 9 ex |
