发明名称 |
CARRIER CONJUGATES OF TNF-PEPTIDES |
摘要 |
The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a modified virus-like particle (VLP) comprising a VLP and a particular peptide derived from a polypeptide from the TNF-superfamily linked thereto. The invention also provides a process for producing the modified VLP. The modified VLPs of the invention are useful in the production of vaccines for the treatment of autoimmune diseases and bone-related diseases and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context. |
申请公布号 |
WO2005117983(A2) |
申请公布日期 |
2005.12.15 |
申请号 |
WO2005EP05936 |
申请日期 |
2005.06.02 |
申请人 |
CYTOS BIOTECHNOLOGY AG;BACHMANN, MARTIN, F.;MAURER, PATRIK;SPOHN, GUNTHER |
发明人 |
BACHMANN, MARTIN, F.;MAURER, PATRIK;SPOHN, GUNTHER |
分类号 |
A61K47/48;C07K14/525;C12N7/04 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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