SYNTHESIS OF AMINO-ALKOXY-HEPTANOIC ALKYL ESTER

摘要

The present invention relates to a process (Mukaiyama Aldol reaction) for thepreparation of compounds of formula (I) wherein R<1> is C1-4 alkyl, C3-6 cycloalkyl-C1-4 alkyl or aryl-C1-4 alkyl; R<2> is C1-4 alkyl, benzyl, substituted benzyl or allyl; R<3> is C1-4 alkyl or allyl; R<4> is C1-4 alkyl, allyl, benzyl or substituted benzyl; R<4>' is benzyl or substituted benzyl; or R<1> and R<4> together form a (CH2)3-group.