发明名称 Methods and compositions for preventing oxidative degradation of proteins
摘要 Methods and compositions for preventing oxidative damage to proteins, particularly antibodies, are provided. The compositions include a combination of metal chelators, such as DTPA, EGTA, and/or DEF, and can further include one or more free radical scavengers, particularly scavengers of oxygen radicals. Methods for enhancing protein stability using the compositions of the invention are also disclosed.
申请公布号 US2005276823(A1) 申请公布日期 2005.12.15
申请号 US20030618350 申请日期 2003.07.11
申请人 CINI JOHN K;NAGI ATHENA D 发明人 CINI JOHN K.;NAGI ATHENA D.
分类号 A61K9/00;A61K47/18;A61K47/26;C07K16/00;C08K5/00;C08K5/17;(IPC1-7):A61K9/00 主分类号 A61K9/00
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