发明名称 TREATMENT WITH GEMCITABINE AND AN EGFR-INHIBITOR
摘要 <p>The present invention provides a method for manufacturing a medicament for treating tumors or tumor metastases, characterized in that a therapeutically effective amount of an EGFR kinase inhibitor and gemcitabine is used, with or without additional agents or treatments, such as other anti-cancer drugs or radiation therapy. The invention also encompasses a pharmaceutical composition that is comprised of an EGFR kinase inhibitor and gemcitabine combination in combination with a pharmaceutically acceptable carrier. A preferred example of an EGFR kinase inhibitor that can be used in practising this invention is the compound erlotinib HCl (also known as Tarceva&lt;TM&gt;).</p>
申请公布号 WO2005117887(A1) 申请公布日期 2005.12.15
申请号 WO2005EP05735 申请日期 2005.05.27
申请人 F. HOFFMANN-LA ROCHE AG;HIGGINS, BRIAN;KOLINSKY, KENNETH 发明人 HIGGINS, BRIAN;KOLINSKY, KENNETH
分类号 A61K31/4706;A61K31/498;A61K31/513;A61K31/517;A61K31/519;A61K31/5377;A61K31/7072;(IPC1-7):A61K31/513;A61K31/537;A61P35/00;A61K31/470 主分类号 A61K31/4706
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