摘要 |
<p>A compound represented by the formula (I):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="40" wi="68" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry> wherein ring A represents an aromatic ring; X represents a bond, oxygen, NR<Sup>4</Sup> (R<Sup>4</Sup> represents hydrogen, a hydrocarbon group, or a heterocyclic group), or alkylene; R<Sup>1</Sup> represents a hydrocarbon group, or a heterocyclic group; R<Sup>2</Sup> represents -COYR<Sup>5</Sup> (Y represents a bond, alkylene, oxygen, sulfur, or NR<Sup>6</Sup> (R<Sup>6</Sup> represents hydrogen, a hydrocarbon group, or a heterocyclic group), and R<Sup>5</Sup> represents a hydrocarbon group, or a heterocyclic group), a hydrocarbon group, or a heterocyclic group; and R<Sup>3</Sup> represents a hydrocarbon group, a heterocyclic group, optionally substituted hydroxy, optionally substituted amino, or -S(O)<Sub>n</Sub>R<Sup>7</Sup> (R<Sup>7</Sup> represents a hydrocarbon group, or a heterocyclic group, and n is 0 to 2), a salt of the compound, or a prodrug or either is useful as an agent for modulating the function of an RFRP receptor.</p> |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
ITOH, FUMIO;HINUMA, SHUJI;KANZAKI, NAOYUKI;BANNO, YOSHIHIRO;YOSHIDA, HIROMI;MATSUMOTO, HIROKAZU |