BENZOFURAN DERIVATIVE

摘要

The present invention is directed to a compound represented by formula (1): <CHEM> (wherein R<1> represents an alkyl group which may have a substituent or an alkenyl group which may have a substituent; and each of R<2> and R<3> represents a hydrogen atom, an alkyl group, a hydroxyalkyl group, a dihydroxyalkyl group, or an alkynyl group, or R<2> and R<3> form, together with the nitrogen atom adjacent thereto, a nitrogen-containing saturated heterocyclic group which may have a substituent) and a drug composition containing the compound. The compound exhibits tumor necrosis factor (TNF- alpha ) production inhibitory effect and improved absorption upon oral administration.