| 发明名称 |
FARNESYL PROTEIN TRANSFERASE INHIBITORS AS ANTITUMOR AGENTS. |
| 摘要 |
<p>Disclosed are novel tricyclic compounds represented by the formula (1.0) and a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising compounds of formula 1.0. Also disclosed are methods of treating cancer using the compounds of formula 1.0.</p> |
| 申请公布号 |
MXPA04008303(A) |
申请公布日期 |
2005.11.23 |
| 申请号 |
MX2004PA08303 |
申请日期 |
2003.02.25 |
| 申请人 |
PHARMACOPEIA DRUG DISCOVERY, INC. |
发明人 |
JAMES, RAY A. |
| 分类号 |
A61K31/496;A61K45/00;A61P35/00;A61P43/00;C07D221/16;C07D401/04;C07D401/06;C07D401/14;C07D521/00;(IPC1-7):A61K31/444;A61K31/495;A61K31/47;A61K31/445;A61K31/505;A61K31/50;C07D405/14;C07D401/12;C07D417/14;C07D409/14 |
主分类号 |
A61K31/496 |
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