| 摘要 |
The present invention provides methods for identifying a subject having an increased risk of developing cancer, for example, breast cancer, comprising determining the presence of the homozygous wild-type genotype of GSTM1, wherein the presence of the homozygous wild-type genotype of GSTM1 identifies a subject with increased risk of cancer. The present invention also provides methods for identifying a subject having a reduced risk of cancer, for example, breast cancer, comprising determining the presence of the homozygous null allele genotype of GSTM1, wherein the presence of the homozygous null allele genotype of GSTM1 identifies a subject with decreased risk of cancer. Also provided are isolated nucleotide sequences and kits for identifying the GSTM1 genotype in a subject.
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