PROCESS FOR PREPARING BRANCHED RIBONUCLEOSIDES FROM 1, 2-ANHYDRORIBOFURANOSE INTERMEDIATES
摘要
<p>A process is provided for the preparation of branched-chain ribonucleosides of formula (I): from the 1,2-anhydroderivatives of formula (II). wherein PG is a hydroxyl protecting group, B is a purine or pyrimidine nucleobase, and R<SUP>1 </SUP>is C<SUB>1-6 </SUB>alkyl. The compounds of formula (I) are inhibitors of HCV polymerase useful in the treatment of HCV infection.</p>
