发明名称 |
INTERNAL IMAGE ANTIBODIES FOR OPTICAL IMAGING AND THERAPY |
摘要 |
Methods using internal image antibodies for photodiagnosis and/or phototherapy. The internal image antibodies are conjugated with a photoactive molecule such as a dye or photosensitizer, to target specific regions, such as biological receptors. The photoactive molecules are then activated for diagnosis or therapy. Advantageously, the internal image antibody is specific for a biological receptor, but does not require isolation of the receptor to prepare the antibody, and provides the desired specificity and selectivity for targeted diagnosis or therapy. |
申请公布号 |
EP1501524(A4) |
申请公布日期 |
2005.11.02 |
申请号 |
EP20020756510 |
申请日期 |
2002.07.18 |
申请人 |
MALLINCKRODT INC. |
发明人 |
RAJAGOPALAN, RAGHAVAN;BUGAJ, JOSEPH, E.;ACHILEFU, SAMUEL, I.;DORSHOW, RICHARD, B. |
分类号 |
A61K39/395;A61K41/00;A61K49/00;A61P7/02;A61P9/10;A61P35/00;A61P43/00;C07K16/28;C07K16/42;C12P21/08;(IPC1-7):A61K35/04;C07K16/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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