发明名称 INTERNAL IMAGE ANTIBODIES FOR OPTICAL IMAGING AND THERAPY
摘要 Methods using internal image antibodies for photodiagnosis and/or phototherapy. The internal image antibodies are conjugated with a photoactive molecule such as a dye or photosensitizer, to target specific regions, such as biological receptors. The photoactive molecules are then activated for diagnosis or therapy. Advantageously, the internal image antibody is specific for a biological receptor, but does not require isolation of the receptor to prepare the antibody, and provides the desired specificity and selectivity for targeted diagnosis or therapy.
申请公布号 EP1501524(A4) 申请公布日期 2005.11.02
申请号 EP20020756510 申请日期 2002.07.18
申请人 MALLINCKRODT INC. 发明人 RAJAGOPALAN, RAGHAVAN;BUGAJ, JOSEPH, E.;ACHILEFU, SAMUEL, I.;DORSHOW, RICHARD, B.
分类号 A61K39/395;A61K41/00;A61K49/00;A61P7/02;A61P9/10;A61P35/00;A61P43/00;C07K16/28;C07K16/42;C12P21/08;(IPC1-7):A61K35/04;C07K16/00 主分类号 A61K39/395
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