发明名称 |
Skin penetration enhancing components |
摘要 |
The present invention relates to a topical formulation for the treatment of a dermatological condition which comprises a macrocyclic lactone antibiotic, immunosuppressive macrolide or a biologically active analogue, derivative or pro-drug thereof; characterized in that it further comprises a permeation modulator and the permeation modulator and the macrocyclic lactone or macrolide or the biologically active analogue, derivative or pro-drug thereof are present in relative amounts such that when a therapeutic amount is applied to the skin a minimal systemic effect is produced. The immunosuppressive macrolide may be sirolimus.
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申请公布号 |
US2005239724(A1) |
申请公布日期 |
2005.10.27 |
申请号 |
US20050153318 |
申请日期 |
2005.06.16 |
申请人 |
WYETH |
发明人 |
ORMEROD ANTHONY D.;WINFIELD ARTHUR |
分类号 |
A61K9/00;A61K9/06;A61K31/436;A61K31/445;A61K31/7048;A61K31/706;A61K38/00;A61K47/10;A61K47/12;A61K47/14;A61P17/00;A61P17/06;A61P17/10;A61P17/14;(IPC1-7):A61K31/704;A61K31/474 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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