发明名称 |
4-heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein |
摘要 |
Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
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申请公布号 |
US6958346(B2) |
申请公布日期 |
2005.10.25 |
申请号 |
US20010999233 |
申请日期 |
2001.10.31 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
STOLTEFUSS JUERGEN;LOEGERS MICHAEL;SCHMIDT GUNTER;BRANDES ARNDT;SCHMECK CARSTEN;BREMM KLAUS-DIETER;BISCHOFF HILMAR;SCHMIDT DELF |
分类号 |
A61K31/47;A61K31/4709;A61P3/06;A61P9/10;A61P31/06;C07D215/20;C07D401/04;C07D405/04;C07D409/04;C07F7/18;(IPC1-7):A61K31/470;C07D401/08 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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