| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new heavy-chain antibody and a single domain heavy-chain antibody useful in the field of immunology. <P>SOLUTION: The functional heavy-chain antibody comprises an amino acid which is neither a charged amino acid nor cysteine at position 45 and comprising an amino acid at position 103 selected from the group consisting of R, G, K, S, and P optionally in combination with Q at position 108. <P>COPYRIGHT: (C)2006,JPO&NCIPI |
