A method of synthesizing a substituted or unsubstituted 4-amino-3-benzimidazolyl quinolinone compound includes reacting a first compound having the formula I with a second compound having the formula II in a suitable solvent in the presence of a sodium or potassium salt of a base. The first compound and the second compound have the following structures where the variables have the values described herein.
申请公布号
WO2005046590(A3)
申请公布日期
2005.10.20
申请号
WO2004US37051
申请日期
2004.11.05
申请人
CHIRON CORPORATION;CAI, SHAOPEI;CHOU, JOYCE;HARWOOD, ERIC;RYCKMAN, DAVID;SHANG, XIAO;ZHU, SHUGUANG;MACHAJEWSKI, TIMOTHY, D.
发明人
CAI, SHAOPEI;CHOU, JOYCE;HARWOOD, ERIC;RYCKMAN, DAVID;SHANG, XIAO;ZHU, SHUGUANG;MACHAJEWSKI, TIMOTHY, D.