| 摘要 |
PROBLEM TO BE SOLVED: To provide an indanol derivative which is an excellent neurokinin receptor antagonist. SOLUTION: This indanol derivative is a compound represented by general formula (I) [wherein R<SP>1</SP>and R<SP>2</SP>are each an optionally substituted (hetero)aryl; R<SP>3</SP>is -CO-R<SP>4</SP>, -CO-O-R<SP>4</SP>or the like; R<SP>4</SP>is an alkyl, a cycloalkyl or the like; A is CH<SB>2</SB>, CO or SO<SB>2</SB>; B is a single bond or the like; D is O or CH<SB>2</SB>; E is an alkylene or an alkenylene; and n is an integer of 1 to 3]. COPYRIGHT: (C)2006,JPO&NCIPI
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