| 发明名称 |
Tri-substituted hetreroaryls and methods of makingand using the same. |
| 摘要 |
Compounds of formula (I) possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of the general formula (I). |
| 申请公布号 |
ZA200407902(B) |
申请公布日期 |
2005.09.22 |
| 申请号 |
ZA20040007902 |
申请日期 |
2004.09.30 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
WEN-CHENG LEE;FENG SHAN;ZHONGLI ZHENG;LIHONG SUN;CLAUDIO CHUAQUI;PETTER, RUSSELL, C. |
| 分类号 |
A61K31/36;A61K31/395;A61K31/41;A61K31/435;A61K31/4439;A61K31/4545;A61K31/517;A61P1/16;A61P9/00;A61P11/00;A61P13/12;A61P17/00;A61P21/00;A61P27/02;A61P35/00;A61P35/04;A61P43/00;C07D401/04;C07D401/14;C07D405/04;C07D405/14;C07D409/04;C07D409/14;C07D453/00;C07D471/04;C07D487/08;C07D519/00 |
主分类号 |
A61K31/36 |
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