发明名称 NOVEL ARYL-CONTAINING 5-ACYLINDOLINONES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS
摘要 The present invention relates to aryl-containing 5-acylindolinones of general formula wherein R<SUP>1 </SUP>to R<SUP>3 </SUP>are defined herein, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, which have valuable pharmacological properties, particularly an inhibiting effect on protein kinases, particularly an inhibiting effect on the activity of glycogen synthase kinase (GSK-3).
申请公布号 CA2559115(A1) 申请公布日期 2005.09.22
申请号 CA20052559115 申请日期 2005.03.05
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 HOERER, STEFAN;HECKEL, ARMIN;UPHUES, INGO;ROTH, GERALD JUERGEN;KLEY, JOERG
分类号 C07D209/34;A61K31/404;C07D403/12;C07D405/06 主分类号 C07D209/34
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