Compounds of formula I in free or salt form, wherein R1, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by of phosphodiesterase type 4 or the down-regulation or inhibition of TNF-alpha release, particularly obstructive or inflammatory airways diseases. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
申请公布号
EP1575950(A1)
申请公布日期
2005.09.21
申请号
EP20030789283
申请日期
2003.12.15
申请人
NOVARTIS AG;NOVARTIS PHARMA GMBH
发明人
DENHOLM, ALASTAIR;KELLER, THOMAS, HUGO;MCCARTHY, CLIVE;PRESS, NEIL, JOHN;TAYLOR, ROGER, JOHN