TAK1-MEDIATED INHIBITION OF OSTEOGENESIS,申请号WO2004IL00286-传众专利搜索

发明名称	TAK1-MEDIATED INHIBITION OF OSTEOGENESIS
摘要	This invention is directed to methods, nucleic acids and compositions in TAK1-mediated regulation of SMAD activity. Promotion of TAK1 interaction with MH2 domains in SMADs negatively regulates SMAD biological activity. BMP-mediated SMAD activity is subject to TAK1 effects.
申请公布号	WO2004087862(A3)	申请公布日期	2005.09.09
申请号	WO2004IL00286	申请日期	2004.03.29
申请人	YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW;GESELLSCHAFT FUR BIOTECHNOLOGISCHE FORSCHUNG (GBF);FLANDERS INTERUNIVERSITY FOR BIOTECHNOLOGY VZW (VIB);K.U. LEUVEN RESEARCH & DEVELOPMENT;GAZIT, DAN;PELLED, GADI;TURGEMAN, GADI;HOFFMANN, ANDREA;GROSS, GERHARD;WODARCZYK, CLAAS;VERSCHUEREN, KRISTIN	发明人	GAZIT, DAN;PELLED, GADI;TURGEMAN, GADI;HOFFMANN, ANDREA;GROSS, GERHARD;WODARCZYK, CLAAS;VERSCHUEREN, KRISTIN
分类号	A61K31/38;A61K48/00;C12N;C12N9/12;C12N15/11;C12N15/85;C12N15/86	主分类号	A61K31/38
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