NUCLEAR TRANSFER PROMOTER FOR Rac PROTEIN AND METHOD OF SCREENING THE SAME
摘要
A nuclear transfer promoter for Rac protein comprising an isoprenoid synthesis inhibitor and/or a geranylgeranyl transferase inhibitor such as an HMG-CoA synthase inhibitor, an HMG-CoA reductase inhibitor, an AMPK activator or a farnesyl pyrophosphoric acid synthase preparation; utilization thereof; a method therefor; a blood vessel remedy comprising the nuclear transfer promoter for Rac protein as the active ingredient; and a method of screening a blood vessel remedy which comprises assaying the ability of Rac protein to transfer into nucleus.
申请公布号
WO2005079846(A1)
申请公布日期
2005.09.01
申请号
WO2005JP02993
申请日期
2005.02.24
申请人
KOWA COMPANY, LTD.;NISSAN CHEMICAL INDUSTRIES, LTD.;KOHRO, TAKAHIDE;SIBASAKI, YOSHIKAZU;HAMAKUBO, TAKAO;KODAMA, TATSUHIKO