发明名称 ARYLIDENE AND FURFURYLIDENE-ACETYL ACETAMIDE AND PROCESS FOR PREPARING THE SAME
摘要 <p>The invention relates to arylidene and furfurylidene acetyl acetamides and to a process for preparing the same. Arylidene and furfurylidene-acetamides have the general formula (I): wherein R1 represents a furfuryl residue or a phenyl residue substituted with a nitro, methoxy or chloro group and R2 represents methyl, methoxy or chloro groups. The process consists in condensing the corresponding aromatic aldehydes or the furfurol with the acetyl-acetarylides, in a molar ratio of 1:1 in polar organic solvents (lowers alcohols), at a temperature of 20...25 C, in the presence of catalytic amounts of benzoic acid and piperidine.</p>
申请公布号 RO120073(B1) 申请公布日期 2005.08.30
申请号 RO19980000181 申请日期 1998.02.04
申请人 INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE CHIMICO-FARMACEUTICA - ICCF 发明人 GUTA RODICA;ILIE CORINA;ANDREESCU DOINA;VISAN VERONICA;PENCU GABRIELA IVONA
分类号 A61K31/00;C07C233/11;C07D307/38;(IPC1-7):C07D307/38 主分类号 A61K31/00
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