发明名称 |
ARYLIDENE AND FURFURYLIDENE-ACETYL ACETAMIDE AND PROCESS FOR PREPARING THE SAME |
摘要 |
<p>The invention relates to arylidene and furfurylidene acetyl acetamides and to a process for preparing the same. Arylidene and furfurylidene-acetamides have the general formula (I): wherein R1 represents a furfuryl residue or a phenyl residue substituted with a nitro, methoxy or chloro group and R2 represents methyl, methoxy or chloro groups. The process consists in condensing the corresponding aromatic aldehydes or the furfurol with the acetyl-acetarylides, in a molar ratio of 1:1 in polar organic solvents (lowers alcohols), at a temperature of 20...25 C, in the presence of catalytic amounts of benzoic acid and piperidine.</p> |
申请公布号 |
RO120073(B1) |
申请公布日期 |
2005.08.30 |
申请号 |
RO19980000181 |
申请日期 |
1998.02.04 |
申请人 |
INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE CHIMICO-FARMACEUTICA - ICCF |
发明人 |
GUTA RODICA;ILIE CORINA;ANDREESCU DOINA;VISAN VERONICA;PENCU GABRIELA IVONA |
分类号 |
A61K31/00;C07C233/11;C07D307/38;(IPC1-7):C07D307/38 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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