发明名称 |
PYRIDAZINONE UREAS AS ANTAGONISTS OF .ALPHA.4 INTEGRINS |
摘要 |
The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives there of and for treating .alpha.4 integrin mediated disorders. More particularly, th e pyridazinone urea compounds of the present invention are .alpha.4.beta.7 integrin inhibitors useful for treating integrin mediated disorders.
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申请公布号 |
CA2555227(A1) |
申请公布日期 |
2005.08.25 |
申请号 |
CA20052555227 |
申请日期 |
2005.02.09 |
申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
HE, WEI;GONG, YONG;BARBAY, KENT |
分类号 |
C07D237/14;A61K31/50;A61K31/501;A61K31/5377;A61P9/10;A61P11/06;A61P29/00;A61P35/04;A61P37/06;A61P37/08;C07D237/16;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/02;C07D413/14;C07D453/02 |
主分类号 |
C07D237/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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