| 发明名称 |
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN METABOTROPIC GLUTAMATE RECEPTOR 5 (MGLUR5) |
| 摘要 |
<p>The invention provides a human mGluR5 which is associated with the cardiovascular diseases, neurological diseases, urological diseases, reproduction disorders and respiratory diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, neurological diseases, urological diseases, reproduction disorders and respiratory diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of mGluR5 as well as pharmaceutical compositions comprising such compounds.</p> |
| 申请公布号 |
WO2005075989(A1) |
申请公布日期 |
2005.08.18 |
| 申请号 |
WO2005EP00346 |
申请日期 |
2005.01.15 |
| 申请人 |
BAYER HEALTHCARE AG;GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS;SUMMER, HOLGER |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS;SUMMER, HOLGER |
| 分类号 |
G01N33/50;G01N33/94;(IPC1-7):G01N33/50;A61K39/00;G01N33/574;A61K38/00;C12Q1/68;C07K14/72;A61K48/00 |
主分类号 |
G01N33/50 |
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