发明名称 |
Multi-stage cascade boosting vaccine |
摘要 |
Humoral and cellular immune responses against tumor cells and infectious agents are induced in a mammal using a vaccine comprising antibodies and anti-idiotype antibodies that mimic an epitope of antigen that is associated with a tumor or infectious agent. Antibodies and cytokines also may be used to amplify the immune cascade. Moreover, antibodies and anti-idiotype antibodies can be used to produce T cells that are not MHC-restricted and that are targeted to tumor cells and infectious agents.
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申请公布号 |
US6926893(B1) |
申请公布日期 |
2005.08.09 |
申请号 |
US20000688089 |
申请日期 |
2000.10.16 |
申请人 |
IMMUNOMEDICS, INC. |
发明人 |
HANSEN HANS J. |
分类号 |
C12N15/09;A61K35/14;A61K35/26;A61K38/00;A61K38/21;A61K39/395;A61K39/44;A61K48/00;A61P31/04;A61P35/00;A61P37/04;C07K16/30;C07K16/42;C07K16/46;C12N5/10;C12P21/08;(IPC1-7):A01N63/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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