| 发明名称 |
Linear basic compounds having NK-2 antagonist activity and formulations thereof |
| 摘要 |
Linear compounds of general formula (I), comprising alpha-alpha-disubstituted amino acid and at least an amino group capable of giving basic characteristics to the compound are disclosed. The compounds are useful for the preparation of medicaments for use in the treatment of respiratory pathologies, ophthalmic diseases, skin diseases, intestinal diseases, gastric diseases, urinary diseases, erectile dysfunctions, diseases of the central nervous system, tumoural pathologies, autoimmunitary diseases or diseases related to AIDS, cardiovascular pathologies, neuritis, neuralgia and treatment of pain, visceralgia and inflammatory processes.
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| 申请公布号 |
NZ533097(A) |
申请公布日期 |
2005.07.29 |
| 申请号 |
NZ20020533097 |
申请日期 |
2002.10.28 |
| 申请人 |
MALESCI ISTITUTO FARMACOBIOLOGICO S |
发明人 |
SISTO, ALESSANDRO;CACIAGLI, VALERIO;ALTAMURA, MARIA;GIOLITTI, ALESSANDRO;FEDI, VALENTINA;GUIDI, ANTONIO;GIANNOTTI,DANILO;HARMAT, NICHOLAS;NANNICINI, ROSSANO;PASQUI, FRANCO;MAGGI, CARLO ALBERTO |
| 分类号 |
A61K38/00;A61K31/38;A61K31/425;A61K38/05;A61P1/00;A61P1/04;A61P9/00;A61P11/06;A61P13/02;A61P15/10;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P25/02;A61P25/04;A61P25/18;A61P25/22;A61P25/24;A61P27/02;A61P27/14;A61P27/16;A61P29/00;A61P31/18;A61P35/00;A61P37/00;A61P37/06;A61P37/08;A61P43/00;C07D333/38;C07D333/70;C07D409/12;C07D413/12;C07D417/12;C07K5/06;C07K5/062;C07K5/065;(IPC1-7):C07K5/062;A61P11/00;A61P13/00;A61P15/00;A61P19/00;A61P27/00 |
主分类号 |
A61K38/00 |
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