发明名称 |
Process for preparation of voglibose |
摘要 |
A process capable of conveniently preparing voglibose at a low cost in a safe process, and an intermediate which can be suitably used in the process and a process for preparing the intermediate are provided. An inositol derivative represented by the formula (VI): wherein Prt is a protecting group of hydroxyl group; a process for preparing the inositol derivative, wherein a cyclohexanone compound represented by the formula (IV): wherein Prt is as defined above, is dihydroxyaminated using a dihydroxyaminating agent and a reducing agent; and a process for preparing voglibose represented by the formula (VIII): wherein the inositol derivative is oxidized to give an inositol compound, and the protecting group, Prt of the inositol compound is deprotected.
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申请公布号 |
US2005165257(A1) |
申请公布日期 |
2005.07.28 |
申请号 |
US20040509059 |
申请日期 |
2005.11.24 |
申请人 |
SAWAI PHARMACEUTICAL CO., LTD. |
发明人 |
SHOGAKI TAKESHI;KAKITA TAKAO;YAGI SUGURU |
分类号 |
C07C213/00;C07C213/02;C07C215/44;C07C217/52;(IPC1-7):C07C213/00 |
主分类号 |
C07C213/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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