ABCA1 STABILIZER

摘要

It is intended to provide an ABCA1 stabilizer focusing on the HDL neogenesis system which is pharmacologically useful as a preventive/remedy for low HDL cholesterolemia. Namely, an ABCA1 stabilizer, which comprises a bisphenol compound selected from among probucol spiroquinone, probucol diphenoquinone and probucol bisphenol as the active ingredient, enables the continuous and stable express of ABCA1 by a mechanism completely different from those in the conventional art, thereby increasing blood HDL level. Therefore, it is useful as a preventive/remedy for low HDL cholesterolemia, arteriosclerosis, etc.