| 发明名称 |
N-PHENYL-(2R,5S)DIMETHYLPIPERAZINE DERIVATIVE |
| 摘要 |
The present invention relates to a novel N-phenyl-(2R,5S)dimethylpiperazine derivatives useful as antiandrogenic agent which exhibits a sufficient prostate gland reducing effect as compared with conventional compounds and are excellent in oral activity. The compound of the present application is useful in preventing or treating prostate cancer, benign prostatic hyperplasia, and the like. The present invention also provides a novel intermediate useful in producing the compound of the present invention.
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| 申请公布号 |
EP1557411(A1) |
申请公布日期 |
2005.07.27 |
| 申请号 |
EP20030764179 |
申请日期 |
2003.07.11 |
| 申请人 |
ASTELLAS PHARMA INC. |
发明人 |
TANIGUCHI, NOBUAKI;IMAMURA, MASAKAZU;HAYAKAWA, MASAHIKO;KAWAGUCHI, KENICHI;KIMURA, TAKENORI;KINOYAMA, ISAO;KAIZAWA, HIROYUKI;OKADA, MINORU;FURUTANI, TAKASHI |
| 分类号 |
C07D213/75;A61K31/495;A61K31/496;A61K31/498;A61K31/506;A61K31/517;A61K31/5377;A61P5/28;A61P13/08;A61P17/08;A61P17/14;A61P35/00;C07D213/84;C07D213/85;C07D239/42;C07D241/04;C07D295/215;C07D401/12;C07D403/12;C07D405/12;C07D417/12;C07D471/04;(IPC1-7):C07D241/04;A61K31/537 |
主分类号 |
C07D213/75 |
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