| 发明名称 |
PROCESS AND SYSTEM FOR CONTROLLED-RELEASE DRUG DELIVERY |
| 摘要 |
A controlled-release dosage form for a phamaceutically-active agent comprises a core, in which the agent is dispersed, surrounded by a diffusion-limiting sleeve. The agent is released at a zero-order or approximately linear rate because the release rate of the agent will be governed entirely by erosion from exposed core surfaces; the surface area of which does not chang e substantially during the release process. Such a product may be made by co- extruding the core and sleeve material and slicing the extrudate.
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| 申请公布号 |
CA2363902(C) |
申请公布日期 |
2005.07.26 |
| 申请号 |
CA20012363902 |
申请日期 |
2001.11.27 |
| 申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
FESSEHAIE, MEBRAHTU;DYAR, STEPHEN CRAIG;MAYASSI, MONZER MICHAEL;GHEBRE-SELLASSIE, ISAAC;WOLDEGABER, HAIMANOT;MOLLAN, MATTHEW JOSEPH, JR. |
| 分类号 |
A61K9/00;A61K9/20;A61K9/22;A61K31/427;A61K47/14;A61K47/32;A61K47/34;A61K47/38;A61P3/10;(IPC1-7):A61K9/22;A61K47/10 |
主分类号 |
A61K9/00 |
| 代理机构 |
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