发明名称 |
INHALANT FORMULATION CONTAINING SULFOALKYL ETHER CYCLODEXTRIN AND CORTICOSTEROID |
摘要 |
An inhalable formulation containing SAE-CD and corticosteroid is provided. T he formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulati on is administered as an aqueous solution, however, it can be stored as a dry powder, ready-to-use solution, or concentrated composition. The formulation is employed in an improved nebulization system for administering corticosteroid by inhalation. SAE-CD present in the formulation significantly enhances the chemical stability of budesonide. A method of administering the formulation by inhalation is provided. The formulation can also be administered by conventional nasal delivery apparatus.
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申请公布号 |
CA2551749(A1) |
申请公布日期 |
2005.07.21 |
申请号 |
CA20042551749 |
申请日期 |
2004.12.31 |
申请人 |
CYDEX, INC. |
发明人 |
MOSHER, GEROLD L.;THOMPSON, DIANE O.;PIPKIN, JAMES D.;ZIMMERER, RUPERT O. |
分类号 |
A61K9/12;A61K9/00;A61K9/08;A61K9/14;A61K31/16;A61K31/57;A61K31/715;A61K47/40;A61K47/48;C08B37/16 |
主分类号 |
A61K9/12 |
代理机构 |
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代理人 |
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地址 |
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