Serological diagnosis of infectious diseases uses microbial antigen immunodetection with monitoring of false positive or negative reactions

摘要

The in vitro serological diagnostic method for detecting the presence and preferably the quantity of immunoglobulins of a microbial antigen characteristic of a microbial agent in a sample of serum taken from a Class M patient, is new. The in vitro serological diagnostic method for detecting the presence and preferably the quantity of immunoglobulins of a microbial antigen characteristic of a microbial agent in a sample of serum taken from a Class M patient includes monitoring of a possible rheumatoid factor in the test sample by placing the sample in contact with a solid support, e.g. of latex micro-balls, on which a first antigen corresponding to a non-specific Class G immunoglobulin has been fixed, is new. The contact is made in the presence of a first detection substance to see if the non-specific Class G immunoglobulin reacts with it.