发明名称 |
SUBSTITUTED THIOPHENES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC REAGENT, AND A MEDICAMENT CONTAINING THE SAME |
摘要 |
The invention relates to substituted thiophene derivatives of formula (I), wherein: R1 to R8 have the meanings as cited in the claims. Medicaments containing compounds of this type are useful in preventing or treating various diseases. Thus, these compounds can be used, among other things, for treating breathing disturbances and snoring, for improving the breathing drive, for treating acute and chronic diseases, diseases triggered by ischemic and/or reperfusion events as well as by proliferative or fibrotic events, for the treatment or prophylaxis of diseases of the central nervous system, lipid metabolism and diabetes, blood clotting and parasitic infection. |
申请公布号 |
HRP20041153(A2) |
申请公布日期 |
2005.06.30 |
申请号 |
HR2004P001153 |
申请日期 |
2004.12.03 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
HANS-JOCHEN LANG;UWE HEINELT;ARMIN HOFMEISTER;KLAUS WIRTH;MICHAEL GEKLE;MARKUS BLEICH |
分类号 |
A61K31/4184;A61K31/454;A61P1/04;A61P3/06;A61P3/10;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P11/00;A61P13/08;A61P13/12;A61P25/00;A61P25/08;A61P25/22;A61P25/24;A61P29/00;A61P33/00;A61P33/06;A61P35/00;A61P39/02;A61P43/00;C07D409/12 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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