发明名称 |
Malleable putty and flowable paste with allograft bone having residual calcium for filling bone defects |
摘要 |
The invention is directed toward a malleable bone putty and a flowable pastel composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing compound of partially demineralized lyophilized allograft bone material having a residual calcium content ranging from 4 to 8% dry weight. The bone powder has a particle size ranging from about 100 to about 800 microns and is mixed in a high molecular weight hydrogel carrier containing a sodium phosphate saline buffer, the hydrogel component of the carrier ranging from about 1.00 to 50% of the composition and having a molecular weight of about at least 700,000 Daltons. The composition has a pH between 6.8-7.4 contains about 25% to about 35% bone powder and can be additionally provided with BMP's.
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申请公布号 |
US6911212(B2) |
申请公布日期 |
2005.06.28 |
申请号 |
US20010983526 |
申请日期 |
2001.10.24 |
申请人 |
MUSCULOSKELETAL TRANSPLANT FOUNDATION |
发明人 |
GERTZMAN ARTHUR A.;SUNWOO MOON H. |
分类号 |
A61K35/32;A61K38/18;A61L24/00;A61L27/36;A61L27/48;A61L27/52;(IPC1-7):A61F2/02;A61F2/28 |
主分类号 |
A61K35/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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