NOVEL PIPERIDINE-SUBSTITUTED INDOLES- OR HETERODERIVATIVES THEREOF

摘要

Accordingly, one object of the present invention are novel piperidine-substituted indoles- or heteroderivatives thereof of the formula(1) wherein R<1>, R<5>, R<6>, A, B, D-E, X-W-V, Y, i, j, n and m are defined as below. Another object of the present invention is to provide agonists or antagonists of CCR-3, or pharmaceutically acceptable salts thereof, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.