CYNOMOLGUS MONKEY DICKKOPF-4, NUCLEOTIDES ENCODING SAME, AND USES THEREOF
摘要
The cynomolgus monkey Dickkopf-4 (cDkk-4) protein, isolated nucleic acid molecules which encode the cDkk-4 protein, and recombinant vectors and hosts comprising DNA encoding the cDkk-4 protein are disclosed. Also disclosed are methods for identifying analytes which interfere with the interaction between the cDkk-4 protein and a homologous or heterologous Dkk receptor and analytes which interfere with the interaction and stimulate bone formation. Analytes identified using the methods are useful for treating osteoporosis and other bone loss disorders.
申请公布号
WO2005049797(A2)
申请公布日期
2005.06.02
申请号
WO2004US37799
申请日期
2004.11.12
申请人
MERCK & CO., INC.;HARADA, SHUN-ICHI;KASPARCOVA, VIERA;GLANTSCHNIG, HELMUT
发明人
HARADA, SHUN-ICHI;KASPARCOVA, VIERA;GLANTSCHNIG, HELMUT