摘要 |
Compositions and methods for the therapy of Inflammatory Bowel Disease (IBD), including Celiac Disease, Crohn's Disease, and Ulcerative Colitis, are disclosed. Illustrative compositions comprise one or more anti-type 1 interferon antagonists, such as anti-type 1 interferon receptor antibody antagonists and fragments thereof, as well as polypeptides and small molecules that inhibit the interaction of type 1 interferon with its receptor (IFNAR). |
申请人 |
MEDAREX, INC.;PICKFORD, LESLEY, B.;BEBBINGTON, CHRISTOPHER, R.;YARRANTON, GEOFFREY, T.;KING, DAVID |
发明人 |
PICKFORD, LESLEY, B.;BEBBINGTON, CHRISTOPHER, R.;YARRANTON, GEOFFREY, T.;KING, DAVID |